Expression of fibroblast activation protein in human pancreatic adenocarcinoma and its clinicopathological significance
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چکیده
منابع مشابه
Expression of LRP16 in pancreatic ductal adenocarcinoma and its clinicopathological significance and prognostic value
Background: The aim of this study is to evaluate the expression of leukemia related protein 16 (LRP16) in pancreatic ductal adenocarcinoma, and analyze its correlation with clinicopathologic features and prognosis. Methods: Immunohistochemistry for LRP16 was performed in 118 cases of pancreatic ductal adenocarcinoma and 34 cases of distal normal pancreatic tissue. The relationship between LRP16...
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OBJECTIVE Particularly interesting new cysteine-histidine rich protein (PINCH) is an important component of the local adhesion complexes and upregulated in several types of malignancies, and involved in the incidence and development of tumours. PINCH expression is also independently correlated with poorer survival in patients with colorectal cancer. However, there is no study of PINCH in gastri...
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Background: Human Cripto-1, a member of the EGF-CFC family, is involved in embryonic development, embryonic stem cell maintenance, and tumor progression. It also participates in multiple cell signaling pathways including Wnt, Notch, and TGF-β. Remarkably, it is expressed in cancer stem cell (CSC) compartments, boosting tumor cell migration, invasion, and angiogenesis. Although Cripto-1 is ...
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The aim of this study was to explore the correlation between the expression levels of Gli1 and p53 in pancreatic ductal adenocarcinoma (PDAC) and its pathological significance. Immunohistochemistry (IHC) was employed to measure the expression level of Gli1 and p53 in 85 sets of paraffin-embedded PDAC and corresponding para-carcinoma tissue specimens. The relationship between these results and t...
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PURPOSE The growth arrest and DNA damage-inducible 45 gene (GADD45a) is one of the downstream mediators of the p53 gene that stimulates DNA excision repair. The present study was designed to assess the clinicopathological significance of GADD45a and p53 in resectable invasive ductal carcinomas (IDCs) of the pancreas. EXPERIMENTAL DESIGN This study included 72 pancreatic IDC patients who recei...
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ژورنال
عنوان ژورنال: World Journal of Gastroenterology
سال: 2012
ISSN: 1007-9327
DOI: 10.3748/wjg.v18.i8.840